Written by
Joel Witts
Agentic Managed Detection and Response (MDR) is a new way of delivering MDR services where autonomous AI agents, as well as human experts, monitor for suspicious activity and take action to stop cyber threats.
Over the past few years, multiple leading MDR providers have moved toward integrating agentic AI into their existing products. Most commonly this has been focused on automating investigations and triage, traditionally very time consuming and repetitive human actions.
With new frontier models able to very quickly spot vulnerabilities and detect malicious behavior, there are even more providers launching autonomous agentic MDR capabilities, including new startups where agentic AI is the basis of the entire MDR capability.
Expert Insights has looked at 10 of the most popular agentic MDR platforms on the market today. We’ve assessed their triage and investigation capabilities, the expertise of the human teams backing them, and the overall quality of the agentic MDR platform.
Like traditional MDR solutions, agentic MDR services manage the process of threat detection and response on behalf of your organization or customers. While traditional MDR services use a mixture of technical threat detection systems and human experts to detect, triage and investigate threats, agentic MDR solutions add autonomous AI agents into the mix. These agents are able to triage and investigate most alerts, while more potentially harmful cases are passed over to human teams for validation.
Agentic MDR is more complex than simply using LLMs to parse logs and explain data. It covers four stages. Agents continuously ingest signals across your network (or your customers'), including ingesting endpoint, cloud, and identity data. This data is automatically correlated, without any human involvement.
If an incident or anomaly is detected, the agent is able to query, assess the context, and form a verdict. In clear-cut cases it can take immediate action like blocking an IP or revoking a session, though clear guardrails should obviously be set to reduce the impact of AI hallucinations. Agents can also escalate incidents to human experts who can then take action when necessary.
Reporting is critical to ensure that agentic workflows are transparent, and that you can understand why decisions were taken.
A high-level comparison of the 10 agentic MDR solutions reviewed in this guide, covering the agentic capabilities each service delivers today.
| Product | Best For | Agentic Triage | Autonomous Investigation | Autonomous Response | Agentic Detection Engineering | Proactive Threat Hunting |
|---|---|---|---|---|---|---|
|
Expel MDR
|
Agentic MDR with human experts kept in the loop
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
|
CrowdStrike Falcon Complete MDR
|
Enterprise agentic MDR at machine speed
|
Yes
|
Yes
|
Yes
|
No
|
Yes
|
|
ReliaQuest GreyMatter
|
Role-based AI teammates across SecOps
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
|
Sophos MDR
|
Explainable AI triage and investigation
|
Yes
|
Yes
|
No
|
No
|
Yes
|
|
Trend Vision One Services MDR
|
Agentic AI on a unified prevention-to-response platform
|
Yes
|
Yes
|
No
|
No
|
Yes
|
|
eSentire Atlas MDR
|
Controlled autonomy across any security stack
|
Yes
|
Yes
|
Yes
|
No
|
Yes
|
|
BitLyft
|
Mid-market Microsoft environments and defense clients
|
No
|
No
|
No
|
No
|
Yes
|
|
Bridewell
|
UK critical national infrastructure and regulated sectors
|
Yes
|
No
|
Yes
|
No
|
Yes
|
|
Binary Defense
|
Decision-ready investigations from an AI-driven SOC
|
Yes
|
Yes
|
No
|
No
|
Yes
|
|
Ontinue
|
Microsoft Defender and Sentinel environments
|
Yes
|
Yes
|
Yes
|
No
|
Yes
|
We looked at 10 agentic MDR solutions, evaluating their capabilities by studying demos, customer conversations and testing firsthand where possible. We focused on the core capabilities of agentic detection, investigation, response, and human expertise wherever possible. This guide was researched and written by Joel Witts and technically reviewed by Craig MacAlpine. Read our full methodology
Expel is a leading provider of agentic managed detection and response (MDR), with threat monitoring for cloud services, identity, email, SaaS apps, Kubernetes, SIEM, and on-prem environments. Ruxie™, Expel’s AI SOC Manager, with AI and agentic capabilities covers each stage of the threat lifecycle: enriching and triaging alerts before analysts touch the queue, correlating alerts across multiple tools and surfaces, applying automated context and classifying alerts for analysts, investigating threats, running response actions, writing new detection rules, and documenting outcomes.
All AI actions are recorded within Expel’s SecOps platform, Workbench™, for a transparent audit trail and explanations. Human cybersecurity experts provide 24×7 monitoring and response, ensuring AI accuracy for judgement calls. Additional strategic advisors support your team with regular collaborative sessions to help you improve your security posture.
Expel’s agents are in production, inside live customer deployments, and every AI decision leaves a fully transparent audit trail in Workbench. The platform deploys in under ten minutes, with an average 15-minute mean time to remediate (MTTR) across high severity incidents. Agents do the volume work and human experts make the final calls. We’d recommend Expel to small to midsized and large enterprises that want AI and agentic speed while keeping people in the loop to ensure accuracy.
Enterprise agentic MDR at machine speed
CrowdStrike Falcon Complete is a leading endpoint detection and response provider with a managed agentic service. It collects and ingests data across your endpoints, identities and clouds, as well as third party cybersecurity services like email security and identity providers. The platform is powered by Charlotte AI, CrowdStrike’s Agentic Analyst. Charlotte AI Detection Triage autonomously assigns a priority level, a true or false positive verdict, and a recommended action to every new detection, operating under customer guardrails. Falcon Complete analysts perform hands-on, end-to-end remediation and Falcon Adversary OverWatch provides 24/7 managed threat hunting across endpoint, identity, and cloud.
CrowdStrike Falcon Complete offers one of the most advanced agentic MDR capabilities on this list. It’s paired with a SOC that can fully remediate threats. The platform is backed by the huge data CrowdStrike has collected across millions of triage decisions. We’d recommend it to enterprises already invested in the Falcon platform that want machine-speed triage without giving up human-led remediation.
Role-based AI teammates across SecOps
ReliaQuest GreyMatter is an agentic AI security operations platform that sits on top of your existing security stack, with 255 integrations across SIEM, EDR, and multi-cloud tools. Its AI Agent, trained on a decade of ReliaQuest incident response data, builds and executes its own investigation workflows dynamically. Six role-based Agentic Teammates work alongside human analysts, drawing on 200+ agent skills to eliminate Tier 1 and Tier 2 SOC work across triage, investigation, containment, and detection engineering.
ReliaQuest has gone further than most with agentic SecOps, and its AI Agent is already deployed across all 1,000+ enterprise customers. We found the Open XDR approach a key differentiator. The agents work across your existing stack instead of requiring a platform migration. We’d recommend GreyMatter to large enterprises that want agentic coverage across every stage of the SOC workflow, including detection engineering.
Explainable AI triage and investigation
Sophos MDR protects 40,000 customers worldwide, making it one of the most widely deployed MDR services on the market. Two production AI agents run inside the Sophos SOC: a Triage Agent and a Case Investigation Agent, which uses sub-agents to plan, execute, and analyze investigations. Every automated action is auditable, with guardrails and escalation paths built in. The service ingests third-party telemetry from 500+ integrations. Human analysts supervise the agents, own every outcome, and deliver proactive threat hunting plus unlimited full-scale incident response.
Sophos has published a full year of production data on its agentic SOC, and the transparency stands out. The 89-second automated resolution time applies only to cases the AI is pre-authorized to close, which we think is the right guardrail model. We’d recommend Sophos MDR to small and mid-sized organizations that want proven agentic speed with unlimited incident response bundled in.
Agentic AI on a unified prevention-to-response platform
Trend Micro’s MDR service is powered by Trend Cybertron, a cybersecurity-specific AI model and agent framework that Trend open-sourced in 2025 to accelerate autonomous security agent development. The platform’s Agentic SIEM replaces manual log and alert monitoring with autonomous data analysis and anomaly detection. The MDR service adds a 24/7/365 human SOC that correlates telemetry across email, endpoint, server, cloud workloads, and network, looks for indicators of compromise, and can respond to prevent threats.
Trend’s differentiator is in its complete MDR platform. It covers prevention, detection, and response in one console, with agentic capabilities baked in. We found the digital twin approach a distinctive take on proactive security that not many other providers offer. Response actions execute through Trend’s own stack, so we’d recommend this service to organizations already on Trend products that want agentic capabilities across the full attack surface.
Controlled autonomy across any security stack
eSentire protects over 2,000 organizations across 80 countries with a multi-signal MDR service. It can ingest endpoint, network, log, cloud, identity, and vulnerability telemetry from your existing stack, including Microsoft Defender XDR and Sentinel. The Atlas platform includes purpose-built AI Operatives that work to continuously monitor, detect, and respond to threats. They can detect new signals in under 30 seconds and can conduct autonomous investigations and responses governed by human guardrails. Atlas AI is trained on more than one million expert-led investigations. Two SOCs in Waterloo and Cork provide 24/7 human coverage, while the Threat Response Unit builds 150+ new proprietary detectors mapped to MITRE ATT&CK every quarter.
eSentire’s guardrails are very effective. Agents act autonomously, but human-judgment controls every decision. Training the AI on a million real investigations provides strong context for even more assurance agents won’t go rogue in your environment. We’d recommend eSentire to mid-sized and large organizations that want agentic MDR across a mixed security stack rather than a single-vendor platform.
Mid-market Microsoft environments and defense clients
BitLyft delivers managed detection and response for small and mid-sized organizations, with a focus on higher education, financial services, manufacturing, and the defense supply chain. Its True MDR service combines managed SIEM, a 24/7 US-based SOC staffed by Tier 3 analysts, and BitLyft AIR, an agentless automation platform. AIR ingests alerts from Microsoft 365, identity providers, and Google Workspace, applies AI-assisted triage and enrichment, then executes automated remediation through native Microsoft Graph API actions. It can suspend accounts, revoke sessions, and isolate resources to contain attackers.
BitLyft is an accessible MDR solution for mid-markets, with published per-user pricing starting at $25.99 per month. Its automation is playbook-driven rather than a fully agentic MDR offering, but it offers 24/7/365 US-based SOC backed by AI-assisted triage. We’d recommend BitLyft to mid-market Microsoft 365 organizations, particularly in defense, education and regulated industries, that want automated response and a US-based human SOC at a transparent price.
UK critical national infrastructure and regulated sectors
Bridewell is a UK-based cybersecurity services company specializing in critical national infrastructure and regulated sectors including energy, aviation, finance, and government. Its Agentic SOC service takes a broker approach: rather than building a single AI platform, Bridewell integrates multiple commercial agentic tools into its Cybiquity platform, sitting above your existing SIEM and EDR. Agents autonomously triage, investigate, and enrich high-volume threats such as phishing and account compromise, with autonomous containment available. Alerts beyond the agents’ capability route automatically into Bridewell’s human-led MDR, so every alert is handled.
Bridewell uses best-of-breed agentic platforms rather than claiming to have built its own, and it routes anything the agents cannot handle to human analysts. For CNI operators facing the UK Cyber Security and Resilience Bill, the audit-ready governance and security-cleared SOC are strong selling points. We’d recommend Bridewell to UK critical infrastructure and regulated organizations that need agentic efficiency with regulator-grade accountability.
Decision-ready investigations from an AI-driven SOC
Binary Defense is an Ohio-based MDR provider. Its NightBeacon platform autonomously investigates and correlates thousands of daily alerts across endpoint, identity, network, and cloud for faster remediation. Each alert is provided with an AI-generated incident narrative, confidence score, attack timeline, evidence, and MITRE ATT&CK mapping, with roughly 80% of the investigation built agentically. Response decisions stay with humans. It also includes AI-powered managed deception and patent-pending Malware Disruption technology with a 90%+ detection rate against known malware families.
Binary Defense’s model is all about removing the frustration of typical alerts, delivering an almost complete threat investigation before the analyst even has to click on a notification. Another strength is the open nature of the platform, you can run it yourself or have the team run it for you, and the platform is vendor agnostic. We’d recommend Binary Defense to mid-sized and large organizations that want autonomous investigation with humans in command of response.
Microsoft Defender and Sentinel environments
Ontinue’s MDR service is built exclusively for the Microsoft security stack: Defender XDR, Sentinel, Azure, and Teams. Its proprietary ION IQ AI runs autonomous threat investigations. For each escalated incident, a multi-agent system aggregates telemetry across logs, identities, endpoints, and cloud. It then executes a test plan and completes a full Tier 2-level investigation in minutes before handing a step-by-step summary to a human expert. It retains a memory of verdicts from every past incident in your environment. Customers can collaborate with the Cyber Defense Center in real time through Microsoft Teams.
Ontinue was among the first MDR providers to put autonomous investigation into production for its entire customer base. It is popular for Microsoft users and supports faster remediation and threat investigations. The service is backed by human experts and it’s a real advantage that you can communicate with experts via Teams. We’d recommend Ontinue to organizations standardized on Microsoft E5 and Defender that want agentic MDR layered onto licensing they already own.
Beyond our top 10, these agentic MDR and AI-assisted SOC solutions are worth considering.
Concierge-model MDR with AI processing telemetry at scale on the Aurora platform.
SMB-focused MDR with AI-assisted triage and one-click remediation.
AI-driven open-XDR MDR with named squad delivery model.
Managed detection and response with Purple AI investigation support on Singularity XDR.
Multi-layer managed detection with AI-assisted triage and deception technology.
AI SOC analyst software that autonomously investigates alerts for in-house teams.
Most agentic MDR services are quote-based, with pricing driven by endpoint or user count, data volumes, and service tier. BitLyft is the only provider on this list with published pricing.
| Product | Starting Price | Billing | Link |
|---|---|---|---|
|
Expel MDR
|
Contact for quote
|
Annual
|
|
|
CrowdStrike Falcon Complete MDR
|
Included with Falcon Complete; contact for quote
|
Annual
|
|
|
ReliaQuest GreyMatter
|
Per endpoint; contact for quote
|
Annual
|
|
|
Sophos MDR
|
Contact for quote
|
Annual
|
|
|
Trend Vision One Services MDR
|
Contact for quote (credit-based platform licensing)
|
Annual
|
|
|
eSentire Atlas MDR
|
Contact for quote
|
Annual
|
|
|
BitLyft
|
From $25.99/user/month
|
Monthly or annual
|
|
|
Bridewell
|
Contact for quote
|
Annual
|
|
|
Binary Defense
|
Contact for quote
|
Annual
|
|
|
Ontinue
|
Contact for quote
|
Annual
|
|
If you're considering rolling out an agentic MDR solution, here are some key features to consider.
AI agents are designed to act autonomously, but they need strong guardrails in place to govern their behavior. Humans should have oversight over the whole loop.
Measure accuracy percentages and containment times against your or your customers' environment during a proof of concept.
You should be able to read the evidence and steps behind any agent verdict, not just the conclusion.
As the service is managed for you, check how AI handles alerts. You may only be able to adjust guardrails by raising a support ticket.
Agentic services are run by the MDR provider. Check that the coverage maps to the services you need in your organization or your customers.
Human security analysts are a critical component of an MDR service. Make sure your provider is trusted and not outsourcing everything to AI.
Agentic features are often bundled, but platform modules, data volumes, and response tiers still move the price.
Agentic MDR is a substantial evolution of the MDR category that is important to be aware of, whether you already have an MDR program in place or are looking to invest for the first time.
It offers real advantages compared to traditional MDR. Threats can now be caught much faster, and investigations are less time consuming. Agents learn and improve over time and can integrate across a broad range of tools.
There are limitations with any agentic MDR service. It’s not always transparent why decisions are made. You don’t own the agentic platform, and you are tied into your vendor’s ecosystem. Costs can escalate as your business grows.
Make sure to consider these points when choosing which agentic MDR provider is the best fit for your business.
Agentic MDR (Managed Detection and Response) is the process of using autonomous AI agents to assist in the process of threat investigation, triage, remediation and reporting, alongside human experts. Agentic MDR is a managed service, meaning it is delivered by a cybersecurity vendor on behalf of your business.
AI agents work autonomously to ingest data from your network to detect potential risks. If an agent catches a threat, it will run a full investigation and triage, including mapping the incident and adding context. It can then remediate, e.g. by isolating an endpoint or revoking a session as per guardrails set by the agentic MDR provider. It can then generate reporting and escalate onto a human for review.
Traditional MDR solutions do use AI as part of the workflow, but this mostly focuses on the detection component, monitoring network data to catch vulnerabilities. Human analysts then pick up the investigation and response component.
Agentic systems use agents to completely automate detection, investigation and response, with human analysts simply reviewing the loop and handling complex cases when needed.
The main benefit of agentic MDR is speed. Agents can work much faster than humans, and they are available 24/7/365. Many vendors are also moving toward an agentic approach, so this will become increasingly common for MDR customers to encounter.
Speed is the number one benefit. Agents are able to respond much faster than humans, with a clearer view of threat data. Theoretically this should translate into faster detection of threats like ransomware. Agentic MDR solutions put the management of threat detection and response into the hands of dedicated experts, who build integrations and deployments for you. They also manage reporting and auditing, which saves you time and cost.
The main limitation of agentic MDR is the risk of hallucination and the lack of control over how agents behave. You are totally reliant on and locked into the agentic MDR provider, so it’s extremely important to have a trusted partner. Custom integrations and detections can be a challenge, as they are with any MDR deployment. And finally, cost can be a concern as your business scales. Agentic capabilities, especially coming via frontier models, can be extremely expensive.
Further reading on endpoint security from Expert Insights — buyers' guides, comparison articles, and platform-specific shortlists.
Joel is the Director of Content and a co-founder at Expert Insights; a rapidly growing media company focused on covering cybersecurity solutions.
He’s an experienced journalist and editor with 8 years’ experience covering the cybersecurity space. He’s reviewed hundreds of cybersecurity solutions, interviewed hundreds of industry experts and produced dozens of industry reports read by thousands of CISOs and security professionals in topics like IAM, MFA, zero trust, email security, DevSecOps and more.
He also hosts the Expert Insights Podcast and co-writes the weekly newsletter, Decrypted. Joel is driven to share his team’s expertise with cybersecurity leaders to help them create more secure business foundations.